13,558 research outputs found

    Sterilizable liquid propulsion system Quarterly progress report, 2 Jan. - 31 Mar. 1967

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    Basic design, component selection, and materials compatibility tests for sterilizable liquid bipropellant propulsion syste

    Sterilizable liquid propulsion system Quarterly progress report, Oct. 1 - Dec. 31, 1967

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    Exposure of assembled and fueled bipropellant liquid rocket propulsion system to ethylene oxide and heat sterilization environment

    DSK1, a novel kinesin-related protein from the diatom Cylindrotheca fusiformis that is involved in anaphase spindle elongation.

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    We have identified an 80-kD protein that is involved in mitotic spindle elongation in the diatom Cylindrotheca fusiformis. DSK1 (Diatom Spindle Kinesin 1) was isolated using a peptide antibody raised against a conserved region in the motor domain of the kinesin superfamily. By sequence homology, DSK1 belongs to the central motor family of kinesin-related proteins. Immunoblots using an antibody raised against a non-conserved region of DSK1 show that DSK1 is greatly enriched in mitotic spindle preparations. Anti-DSK1 stains in diatom central spindle with a bias toward the midzone, and staining is retained in the spindle midzone during spindle elongation in vitro. Furthermore, preincubation with anti-DSK1 blocks function in an in vitro spindle elongation assay. This inhibition of spindle elongation can be rescued by preincubating concurrently with the fusion protein against which anti-DSK1 was raised. We conclude that DSK1 is involved in spindle elongation and is likely to be responsible for pushing hal-spindles apart in the spindle midzone

    Diffraction efficiency of strong volume holograms

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    We investigate the diffraction efficiency of strong volume holograms in which the coupling parameter is several times that needed for maximum diffraction efficiency. We discuss the implications of our findings on photorefractive implementations of various neural network systems

    Classical Robustness of Quantum Unravellings

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    We introduce three measures which quantify the degree to which quantum systems possess the robustness exhibited by classical systems when subjected to continuous observation. Using these we show that for a fixed environmental interaction the level of robustness depends on the measurement strategy, or unravelling, and that no single strategy is maximally robust in all ways.Comment: 8 Pages, 2 figures, Version 2. Minor changes to wording for clarification and some references added. Accepted for publication in Europhysics Letter

    Efficacy and Safety of Pediatric Critical Care Physician Telemedicine Involvement in Rapid Response Team and Code Response in a Satellite Facility

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    OBJECTIVES: Satellite inpatient facilities of larger children's hospitals often do not have on-site intensivist support. In-house rapid response teams and code teams may be difficult to operationalize in such facilities. We developed a system using telemedicine to provide pediatric intensivist involvement in rapid response team and code teams at the satellite facility of our children's hospital. Herein, we compare this model with our in-person model at our main campus. DESIGN: Cross-sectional. SETTING: A tertiary pediatric center and its satellite facility. PATIENTS: Patients admitted to the satellite facility. INTERVENTIONS: Implementation of a rapid response team and code team model at a satellite facility using telemedicine to provide intensivist support. MEASUREMENTS AND MAIN RESULTS: We evaluated the success of the telemedicine model through three a priori outcomes: 1) reliability: involvement of intensivist on telemedicine rapid response teams and codes, 2) efficiency: time from rapid response team and code call until intensivist response, and 3) outcomes: disposition of telemedicine rapid response team or code calls. We compared each metric from our telemedicine model with our established main campus model. MAIN RESULTS: Critical care was involved in satellite campus rapid response team activations reliably (94.6% of the time). The process was efficient (median response time 7 min; mean 8.44 min) and effective (54.5 % patients transferred to PICU, similar to the 45-55% monthly rate at main campus). For code activations, the critical care telemedicine response rate was 100% (6/6), with a fast response time (median 1.5 min). We found no additional risk to patients, with no patients transferred from the satellite campus requiring a rapid escalation of care defined as initiation of vasoactive support, greater than 60 mL/kg in fluid resuscitation, or endotracheal intubation. CONCLUSIONS: Telemedicine can provide reliable, timely, and effective critical care involvement in rapid response team and Code Teams at satellite facilities

    Frequency Diverse Array Radar: Signal Characterization and Measurement Accuracy

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    Radar systems provide an important remote sensing capability, and are crucial to the layered sensing vision; a concept of operation that aims to apply the right number of the right types of sensors, in the right places, at the right times for superior battle space situational awareness. The layered sensing vision poses a range of technical challenges, including radar, that are yet to be addressed. To address the radar-specific design challenges, the research community responded with waveform diversity; a relatively new field of study which aims reduce the cost of remote sensing while improving performance. Early work suggests that the frequency diverse array radar may be able to perform several remote sensing missions simultaneously without sacrificing performance. With few techniques available for modeling and characterizing the frequency diverse array, this research aims to specify, validate and characterize a waveform diverse signal model that can be used to model a variety of traditional and contemporary radar configurations, including frequency diverse array radars. To meet the aim of the research, a generalized radar array signal model is specified. A representative hardware system is built to generate the arbitrary radar signals, then the measured and simulated signals are compared to validate the model. Using the generalized model, expressions for the average transmit signal power, angular resolution, and the ambiguity function are also derived. The range, velocity and direction-of-arrival measurement accuracies for a set of signal configurations are evaluated to determine whether the configuration improves fundamental measurement accuracy
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